Equine Neuromuscular

Contact Us

Veterinary Diagnostic Laboratory
University of Minnesota
1333 Gortner Avenue
St. Paul, MN 55108-1098

nmdl@umn.edu

Phone: 612-625-8787
Toll Free: 800-605-8787
Fax: 612-624-8707

Updated April 4, 2019

The Equine Neuromuscular and Genetics Diagnostic Laboratory is dedicated to providing the most accurate diagnosis and optimal treatment of muscle disorders in horses. We offer genetic and muscle biopsy testing for a variety of diseases.

Genetic Testing

  • Polysaccharide storage myopathy
    • Type 1 PSSM causes muscle soreness and tying up in over 20 breeds.
    • Type 2 PSSM can cause similar symptoms to type 1. A muscle biopsy is required to diagnose type 2 PSSM. Michigan State University performs the muscle biopsy.
  • Malignant hyperthermia (MH)
    • Malignant hyperthermia occurs in quarter horses and paints and can cause signs of tying up, elevated body temperature, sweating, and anesthetic reactions. It can occur together with type 1 PSSM giving particularly severe signs of tying up.

Please see submission information for genetic testing. 

For clinical information on equine neuromuscular diseases, visit The Equine Neuromuscular Diagnostic Laboratory website

For information on equine genetic research, visit The Equine Genetics and Genomics Laboratory website

 

Muscle Biopsy Testing

As of December 21, 2015, muscle biopsy testing will no longer be offered at the University of Minnesota and will transition with Dr. Valberg to Michigan State University beginning January 4, 2016.

Submission information at Michigan State

Services & Fees

Note on days tested and turnaround times: Samples must be received at least one business day before the scheduled testing day. Samples may not always be tested on the first scheduled day after they arrive, but testing will usually be completed within the posted turnaround time.

To order:

Step 1:

Submission form

Step 2:

Place order

Specimen Requirements:

1) 3-7 ml whole blood 2) 20 hair roots 

Shipping Container:

1) EDTA tube 2) sealed envelope or zip lock bag (hairs should be gathered together securely using a piece of tape or a rubber band)

Coolant:
1) frozen gel packs 2) none
Fee:
65.00
Days Tested:
Every other W
Turnaround Time:
7-14 bus. days
Comments:

Results reported on Mondays.  Samples should be received by the previous Tuesday.    This mutation is found in Quarter Horses and Paint horses.  It may cause tying-up and will make signs of tying-up more severe in some horses with PSSM.  The mutation also causes postanesthetic myopathy.

Specimen Requirements:

1) 3-7 ml whole blood 2) 20 hair roots

Shipping Container:

1) EDTA tube 2) sealed envelope or zip lock bag (hairs should be gathered together securely using a piece of tape or a rubber band)

Coolant:
1) frozen gel packs 2) none
Fee:
65.00
Days Tested:
W
Turnaround Time:
7-14 bus. days
Comments:

Results reported on Mondays. Samples should be received by the previous Tuesday. See the Equine Neuromuscular home page for more information on submitting for this test.   This mutation is responsible for tying up due to PSSM in >90% of draft horses, >70% of Quarter Horses, Paints and Appaloosas, and has also been identified in Warmbloods, Hafflingers, Morgans, Tennessee Walking Horses, Rocky Mountain Spotted Horses and Mustangs.